Missouri Governor Mike Parson signed Executive Order 20-06 on Friday, March 27, 2020, to mobilize the Missouri National Guard to assist with the response to COVID-19 and increase coordination among state government partners.

Major Employers

Major Employers

With an estimated 9,000 public and private employers in St. Charles County in 2020, some of our largest for-profit organizations include:

  • General Motors
  • CitiMortgage
  • MasterCard Worldwide
  • The Boeing Company
  • Ameristar Casino Resort Spa
  • Enterprise Holdings
  • True Manufacturing
  • Verizon
  • GC Services
  • Client Services
  • NISC
  • Nike Air MI


Some of our largest not-for-profit employers in St. Charles County for 2020 include:

  • Wentzville School District
  • Fort Zumwalt School District
  • Francis Howell School District
  • SSM St. Joseph Hospital – St. Charles
  • Barnes-Jewish St. Peters Hospital
  • St. Charles County Government
  • St. Charles Community College
  • St. Charles City School District
  • SSM St. Joseph Hospital – Lake Saint Louis
  • City of O’Fallon
  • Lindenwood University
  • Progress West Hospital



2019 Major Employers PDF